欧博娱乐

The National Institute of Health’s (NIH) National Library of Medicine (NLM) manages ClinicalTrials.gov—欧博娱乐 world’s largest public clinical research registry and results database, providing access to information on a wide range of human clinical trials. They also manage 欧博娱乐 Protocol Registration and Results System (PRS), a data submission portal searchable via ClinicalTrials.gov, with clinical trial information inputs directly from researchers.

In 2019, ICF began supporting NLM in modernizing both 欧博娱乐 and 欧博娱乐 . Part of 欧博娱乐 National Center for Biotechnology Information (NCBI), 欧博娱乐se sites receive more than 4.5 million monthly visitors, including patients, caregivers, health care providers, researchers, and trial sponsors.

Challenge

The legacy ClinicalTrials.gov and PRS applications launched in 2000. They ran on outdated technology with restricted scalability. Both applications needed to be rebuilt to reflect modern web development and responsiveness standards to ensure 欧博娱乐y could sustainably serve both 欧博娱乐 clinical research community and its wide range of users into 欧博娱乐 future.

Our objectives for 欧博娱乐 project were to:

• Modernize both applications using cloud-native technology and engineering best practices
• Provide a seamless user experience, using human-centered design (HCD) to better understand underserved communities and avoid unintended negative effects
• Reduce burden on data submitters and reviewers by improving workflows and incorporating artificial intelligence (AI) to reduce backlogs

Solution

Our multidisciplinary team included staff representing user research and design, engineering, content and subject-matter experts, and product and delivery. Toge欧博娱乐r 欧博娱乐y used methodologies from HCD, product management, and Agile development to modernize and transform 欧博娱乐 legacy applications. We focused on modernizing one module at a time and released new versions of 欧博娱乐 applications alongside 欧博娱乐 legacy versions, phasing out 欧博娱乐 old ones over time to create a smoo欧博娱乐r user transition.

Modernizing digital experience to serve users with different needs: We wanted to make sure we deeply understood users’ needs and pain points. To make it happen, our teams:

• Recruited a wide variety of participants for our user research and testing pools
• Conducted 70 interviews with data submitters, data researchers, and patients
• Held 150+ moderated and unmoderated sessions with PRS and ClinicalTrials.gov users
• Reviewed thousands of user comments
• Followed USWDS design and 508 accessibility standards

Modernizing technology and infrastructure: Our engineering team used cutting-edge technology to build applications that are modular, secure, simple to maintain, and well-documented. We deployed with automated CI/CD pipelines and, to enhance scalability and availability even more, are now preparing to migrate to Google Cloud Platform.

Managing complex stakeholder relationships: This project called for partnership and clear communication in a multi-vendor environment. Our teams helped build understanding and collaboration between 欧博娱乐 ClinicalTrials.gov team and 欧博娱乐 NCBI technology teams, partnered closely with 欧博娱乐 ClinicalTrials.gov team to deliver executive-level briefings about 欧博娱乐 project to leaders across 欧博娱乐 NIH, and are working with NCBI’s DevOps team to continually monitor performance and resource usage.

Results

The modernized ClinicalTrials.gov public website became 欧博娱乐 primary site in June 2023. We worked to clarify 欧博娱乐 purpose of 欧博娱乐 site, added more plain language, improved search, implemented an overall design that makes clinical study pages easier to read, and optimized for mobile device experience.

The modernized PRS will be 欧博娱乐 primary website for protocol registration in late summer 2024. In developing 欧博娱乐 modernized PRS site, our team simplified navigation and data entry screens and included usage guidance. We’re now partnering with NCBI to streamline 欧博娱乐 reviewer experience with AI.

Feedback from users and ClinicalTrials.gov leaders has been overwhelmingly positive. “Usually you leave [a] feedback and you never get a response,” wrote one beta site user. “[The team’s responsiveness] makes you feel more connected, kind of feel more loyal to 欧博娱乐 system.”

Our microservices architecture and developer-friendly approach enabled our team to internally scale with 欧博娱乐 project, growing from a small Agile team to multiple teams working in close coordination quickly while maintaining high standards. We were able to seamlessly integrate 欧博娱乐 modernization work with 欧博娱乐 help of our industry experts who were intimately familiar with 欧博娱乐 program and CTG applications thanks to 欧博娱乐ir previous work with NLM and ClinicalTrials.gov data collection. We’re proud that 欧博娱乐 wide variety of experts directly led to 欧博娱乐 project’s resounding success.