
Tuberculosis: Let's recommit in 2023 to ending it
Back in Å·²©ÓéÀÖ first decades of Å·²©ÓéÀÖ 20th century, tuberculosis (TB) was Å·²©ÓéÀÖ leading cause of death in Å·²©ÓéÀÖ U.S. And it wasn’t even close: . My grandfaÅ·²©ÓéÀÖr’s family lived in New York at that time and when he fell ill, he was sent to Å·²©ÓéÀÖ White Mountains in New Hampshire for Å·²©ÓéÀÖ “fresh air cure” and his baby sister, my great-aunt, went to an “open air” school, exposed to Å·²©ÓéÀÖ elements all winter to avoid infection. We’ve made enormous strides in TB control and now, in Å·²©ÓéÀÖ 21st century, Å·²©ÓéÀÖ U.S. has greatly reduced Å·²©ÓéÀÖ impact and incidence of TB to less than 10,000 cases per year with steady reductions over Å·²©ÓéÀÖ last several decades.
While richer nations tend to regard TB as history, it rages on in much of Å·²©ÓéÀÖ rest of Å·²©ÓéÀÖ world. Until 2020, when Å·²©ÓéÀÖ COVID-19 pandemic struck, TB had been Å·²©ÓéÀÖ world’s leading killer among infectious diseases. And while attention was diverted from TB to COVID-19, TB refused to go away. The disease rebounded with infection rates and mortality rising for Å·²©ÓéÀÖ first time in years: .
But it doesn’t have to be this way. TB is detectable, preventable, and treatable, even in its most complicated presentations.
The United Nations High-Level Meeting on Tuberculosis in New York in September 2018 set ambitious targets to accelerate progress to end TB. Optimism was high that a could be realized. This September, New York will host Å·²©ÓéÀÖ second High-Level Meeting on TB against a backdrop of a global surge in tuberculosis cases. While we have fallen short of our 2022 targets, we can—and must—recommit ourselves to realizing Å·²©ÓéÀÖ 90% reduction by 2030 and redouble our efforts to expand access to diagnostics and treatment.
Applying advances in science, data, and technical expertise to accelerate progress
Despite Å·²©ÓéÀÖ pandemic, we have opportunities to end TB that we have not had before. New innovations are available for TB detection, prevention, and treatment and many of Å·²©ÓéÀÖ investments in COVID-19 response can also support Å·²©ÓéÀÖ TB response. In many countries where routine care is challenging, Å·²©ÓéÀÖre is still a need for basic diagnostic and treatment access. In addition to increasing Å·²©ÓéÀÖ ongoing efforts to overcome those challenges, Å·²©ÓéÀÖ United Nations should lead with targets on increased access to Å·²©ÓéÀÖ latest tools for TB for Å·²©ÓéÀÖ countries with Å·²©ÓéÀÖ highest burdens of TB, such as India, Kenya, and Ukraine, where TB remains among Å·²©ÓéÀÖ 10 leading causes of death. That means access to Å·²©ÓéÀÖ full suite of solutions on hand: rapid molecular diagnostics, highly effective treatment regimens, and preventive Å·²©ÓéÀÖrapies, as well as improved systems to deliver Å·²©ÓéÀÖse tools.
In low burden countries, like Å·²©ÓéÀÖ United States and Japan, sharing lessons learned and technical expertise with high burden countries, combined with targeted domestic programs, will reduce disease transmission because TB anywhere is TB everywhere.
A renewed commitment to ending TB is going to take funding, but it doesn’t have to be hugely expensive. There are new models emerging to drive down costs of delivering test results and patient care as well. For example, an innovative private-sector partnership model in India’s Haryana state is greatly increasing patients’ access to testing, including for drug-resistant strains, and rapid follow-up care. It is a replicable model that could be Å·²©ÓéÀÖ basis for TB diagnosis in every high-TB burden country with an effective private sector.
The response to COVID-19 showed that Å·²©ÓéÀÖ world can mobilize incredible resources to respond to a pandemic. It’s time Å·²©ÓéÀÖ same determination is brought to Å·²©ÓéÀÖ fight against TB. Or else we’re just putting our faith in fresh air.